Per-Olof Berggren Selected Research

2-(2-imidazolin-2-yl)-1-phenyl-1H-indole

1/2016

The imidazoline compound RX871024 promotes insulinoma cell death independent of AMP-activated protein kinase inhibition.

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Per-Olof Berggren Research Topics

Disease

18	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2002
18	Insulin Resistance 12/2021 - 09/2010
13	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2021 - 07/2004
10	Inflammation (Inflammations) 06/2022 - 09/2010
9	Obesity 12/2021 - 09/2010
8	Neoplasms (Cancer) 01/2020 - 04/2009
7	Hyperglycemia 01/2020 - 08/2005
5	Hypoglycemia (Reactive Hypoglycemia) 01/2016 - 08/2003
4	Metabolic Diseases (Metabolic Disease) 01/2021 - 01/2014
4	Hyperinsulinism (Hyperinsulinemia) 12/2019 - 05/2008
4	Diabetes Mellitus 09/2018 - 12/2002
4	Insulinoma 01/2016 - 05/2002
3	Acquired Immunodeficiency Syndrome (AIDS) 01/2022 - 04/2009
3	Hypoxia (Hypoxemia) 01/2022 - 01/2018
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2019 - 01/2013
3	Glucose Intolerance 04/2016 - 07/2014
2	Acute Kidney Injury (Acute Renal Failure) 04/2022 - 11/2021
2	Prediabetic State (Prediabetes) 03/2022 - 06/2011
2	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2022 - 04/2016
2	Autoimmune Diseases (Autoimmune Disease) 01/2019 - 03/2013
2	Muscular Atrophy (Muscle Atrophy) 12/2017 - 04/2013
2	Blindness (Hysterical Blindness) 12/2016 - 01/2016
2	Body Weight (Weight, Body) 01/2013 - 09/2010
1	Periodontal Diseases (Periodontal Disease) 06/2022
1	Pancreatitis 01/2022
1	Morbid Obesity 01/2022
1	Adenoviridae Infections (Adenovirus Infections) 10/2020
1	Congenital Abnormalities (Deformity) 01/2020
1	Primitive Neuroectodermal Tumors (PNET) 10/2019
1	Overweight 01/2019
1	Atherosclerosis 01/2018
1	Weight Gain 01/2018
1	Neuroinflammatory Diseases 01/2018
1	Mental Disorders (Mental Disorder) 01/2018
1	Schizophrenia (Dementia Praecox) 12/2017

Drug/Important Bio-Agent (IBA)

29	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2002
23	Insulin (Novolin)FDA Link 01/2020 - 07/2004
8	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2010
7	CytokinesIBA 06/2022 - 09/2006
5	Apolipoprotein C-IIIIBA 12/2021 - 07/2004
5	Glucagon (Glukagon)FDA Link 01/2020 - 06/2008
4	Adenosine Triphosphate (ATP)IBA 01/2020 - 04/2009
3	Blood Glucose (Blood Sugar)IBA 01/2020 - 01/2016
3	LipidsIBA 01/2019 - 03/2010
3	ApolipoproteinsIBA 01/2017 - 06/2011
3	ImidazolinesIBA 01/2016 - 01/2002
3	Nonesterified Fatty Acids (NEFA)IBA 09/2015 - 04/2015
2	A-Form DNA (A-DNA)IBA 04/2022 - 11/2021
2	MicroRNAs (MicroRNA)IBA 01/2022 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 12/2021 - 08/2015
2	Oxygen (Dioxygen)IBA 01/2020 - 01/2018
2	Pharmaceutical PreparationsIBA 10/2019 - 08/2003
2	Estrogens (Estrogen)FDA Link 01/2019 - 01/2013
2	Estrogen Receptor alphaIBA 01/2019 - 01/2013
2	Protein Tyrosine PhosphatasesIBA 12/2017 - 04/2013
2	Insulin Receptor Substrate ProteinsIBA 12/2017 - 04/2013
2	AMP-Activated Protein KinasesIBA 12/2017 - 01/2016
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2017 - 09/2010
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2017 - 09/2015
2	nephrinIBA 04/2016 - 01/2010
2	CholesterolIBA 09/2015 - 01/2013
2	Amino Acids FDA Link 12/2014 - 05/2002
2	LeptinIBA 12/2013 - 07/2013
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 12/2009 - 09/2006
1	Interleukin-10 (Interleukin 10)IBA 06/2022
1	HydrogelsIBA 06/2022
1	DNA (Deoxyribonucleic Acid)IBA 06/2022
1	Uric Acid (Urate)IBA 03/2022
1	NPHS2 proteinIBA 01/2022
1	2- amino- 3- (4'- N,N- bis(2- chloroethyl)amino)phenylpropionic acid N-oxideIBA 01/2022
1	Small Interfering RNA (siRNA)IBA 01/2022
1	Insulin ReceptorIBA 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Protein Isoforms (Isoforms)IBA 01/2021
1	Antiviral Agents (Antivirals)IBA 11/2020
1	RotenoneIBA 10/2020
1	Streptozocin (Streptozotocin)FDA Link 01/2020
1	Clodronic Acid (Clodronate)IBA 12/2019
1	Heparin-binding EGF-like Growth Factor (HB-EGF)IBA 12/2019
1	Macrophage Colony-Stimulating FactorIBA 12/2019
1	Immunosuppressive Agents (Immunosuppressants)IBA 01/2019
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2019
1	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2019
1	CarbohydratesIBA 01/2019
1	PolyphenolsIBA 09/2018
1	Fenofibrate (CiL)FDA LinkGeneric 09/2018
1	Hypoxia-Inducible Factor 1IBA 01/2018
1	Kynurenic Acid (Kynurenate)IBA 01/2018
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	Nuclear Proteins (Protein, Nuclear)IBA 01/2018
1	Tryptophan (L-Tryptophan)FDA Link 01/2018
1	KynurenineIBA 01/2018
1	dihydrotanshinone IIBA 12/2017

Therapy/Procedure

6	Transplantation 10/2020 - 08/2005
3	Immunotherapy 06/2022 - 01/2020
3	Therapeutics 01/2021 - 08/2005
2	Glycemic Control 01/2017 - 04/2015
2	Intraperitoneal Injections 08/2015 - 03/2010
1	Bariatric Surgery 01/2022
1	Islets of Langerhans Transplantation 01/2020